Sermorelin Acetate 2 sizes RESEARCH USE ONLY BLACK BOX BIOTECHNOLOGY · SMO5

Sermorelin Acetate

Also known as: GHRH (1-29) NH2 · GRF 1-29 · Geref
Growth Hormone Axis In stock Box of 10 vials 2 references

The native 29-residue active fragment of GHRH.

Available sizes

SKUPer vialPack
SMO5 5 mg 10 vials / box
SMO10 10 mg 10 vials / box

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Sermorelin is the acetate salt of GHRH(1-29)-NH2, the shortest fragment of growth-hormone-releasing hormone that retains full biological activity 2. It stimulates GH secretion from pituitary somatotrophs via the GHRH receptor.

Sermorelin has been used clinically both as a diagnostic agent for GH-secretory capacity and as a treatment in children with GH deficiency; a review of its use summarises the clinical pharmacology 1.

At a glance

  • Native GHRH (1-29) — reference GHRH-receptor agonist
  • Clinically characterised in GH-deficiency diagnosis
  • 5 mg and 10 mg vials
Research use only. All products are sold strictly for laboratory research and development purposes. They are not intended for human or veterinary use, diagnosis, treatment, cure or prevention of any disease. Not for human consumption. Summaries above describe published findings in laboratory and clinical research models and do not constitute claims about this product.
Form
Lyophilized powder
Purity
HPLC-verified — Certificate of Analysis available on request
Pack size
Box of 10 vials
Storage
Lyophilized: −20 °C, protected from light (2–8 °C short-term). Reconstituted: 2–8 °C.
Sequence
Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2
Formula
C149H246N44O42S
Mol. weight
3357.9 g/mol
CAS No.
86168-78-7

Sequence, formula and CAS data are provided for identification. Batch-specific purity, mass-spec and HPLC data are on the Certificate of Analysis — ask for it with your order.

  1. Prakash A, Goa KL Sermorelin: a review of its use in the diagnosis and treatment of children with idiopathic growth hormone deficiency. BioDrugs. 1999;12(2):139-57.
  2. Grossman A, Savage MO, Besser GM Growth hormone releasing hormone. Clin Endocrinol Metab. 1986;15(3):607-27.

Citations retrieved from PubMed (NCBI). Links open the publisher record via DOI and the PubMed abstract.

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