Cognitive
DSIP
Also known as: Delta sleep-inducing peptide · Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
Cognitive & Sleep In stock Box of 10 vials 2 references
Nonapeptide first isolated from rabbit brain for its ability to induce delta-wave sleep.
Available sizes
| SKU | Per vial | Pack | |
|---|---|---|---|
| DS5 | 5 mg | 10 vials / box | |
| DS10 | 10 mg | 10 vials / box | |
| DS15 | 15 mg | 10 vials / box |
Order DSIP
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DSIP is a nine-residue neuropeptide (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) originally isolated from the cerebral venous blood of rabbits in slow-wave sleep. It was named for its ability to enhance delta-EEG activity and sleep spindles after intraventricular infusion 1.
DSIP is one of the classic examples of a small peptide that crosses the blood–brain barrier, and it remains a reference compound in studies of peptide BBB transport 2 and sleep–stress regulation.
At a glance
- Classic sleep-regulating neuropeptide (PNAS, 1977)
- Studied in sleep, stress and pain modulation
- 5, 10 and 15 mg vials
Research use only. All products are sold strictly for laboratory research and development purposes. They are not intended for human or veterinary use, diagnosis, treatment, cure or prevention of any disease. Not for human consumption. Summaries above describe published findings in laboratory and clinical research models and do not constitute claims about this product.
- Form
- Lyophilized powder
- Purity
- HPLC-verified — Certificate of Analysis available on request
- Pack size
- Box of 10 vials
- Storage
- Lyophilized: −20 °C, protected from light (2–8 °C short-term). Reconstituted: 2–8 °C.
- Sequence
- Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
- Formula
- C35H48N10O15
- Mol. weight
- 848.8 g/mol
- CAS No.
- 62568-57-4
Sequence, formula and CAS data are provided for identification. Batch-specific purity, mass-spec and HPLC data are on the Certificate of Analysis — ask for it with your order.
- Schoenenberger GA, Monnier M Characterization of a delta-electroencephalogram (-sleep)-inducing peptide. Proc Natl Acad Sci U S A. 1977;74(3):1282-6.
- Banks WA Peptides and the blood-brain barrier. Peptides. 2015;72:16-9.
Citations retrieved from PubMed (NCBI). Links open the publisher record via DOI and the PubMed abstract.
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