Skin
SNAP-8
Also known as: Acetyl octapeptide-3 · Acetyl glutamyl heptapeptide-3
Skin & Cosmetic In stock Box of 10 vials 1 reference
SNAP-25-mimicking octapeptide developed as a topical alternative to botulinum-type activity.
Available sizes
| SKU | Per vial | Pack | |
|---|---|---|---|
| NP810 | 10 mg | 10 vials / box | |
| NP820 | 20 mg | 10 vials / box |
Order SNAP-8
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SNAP-8 (acetyl octapeptide-3) is an eight-residue elongation of the hexapeptide Argireline (acetyl hexapeptide-3). Both mimic the N-terminus of SNAP-25, competing for a position in the SNARE complex and thereby attenuating neurotransmitter vesicle release at the neuromuscular junction.
The parent hexapeptide was shown to inhibit SNARE-complex formation and catecholamine release in vitro, and reduced wrinkle depth by up to 30% in a 30-day topical study 1. SNAP-8 was subsequently developed as a more potent extension of the same sequence.
At a glance
- SNAP-25 mimetic; SNARE-complex modulator
- Cosmetic anti-wrinkle research peptide
- 10 mg and 20 mg vials
Research use only. All products are sold strictly for laboratory research and development purposes. They are not intended for human or veterinary use, diagnosis, treatment, cure or prevention of any disease. Not for human consumption. Summaries above describe published findings in laboratory and clinical research models and do not constitute claims about this product.
- Form
- Lyophilized powder
- Purity
- HPLC-verified — Certificate of Analysis available on request
- Pack size
- Box of 10 vials
- Storage
- Lyophilized: −20 °C, protected from light (2–8 °C short-term). Reconstituted: 2–8 °C.
- Sequence
- Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2
- Formula
- C41H70N16O16S
- Mol. weight
- 1075.2 g/mol
- CAS No.
- 868844-74-0
Sequence, formula and CAS data are provided for identification. Batch-specific purity, mass-spec and HPLC data are on the Certificate of Analysis — ask for it with your order.
- Blanes-Mira C, Clemente J, Jodas G, et al. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int J Cosmet Sci. 2002;24(5):303-10.
Citations retrieved from PubMed (NCBI). Links open the publisher record via DOI and the PubMed abstract.
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